Probucol Inhibits ABCA1-Mediated Cellular Lipid Efflux
نویسندگان
چکیده
منابع مشابه
Probucol inhibits ABCA1-mediated cellular lipid efflux.
OBJECTIVE ATP-binding cassette transporter A1 (ABCA1) mediates the efflux of lipids from cells to lipid-poor apolipoproteins. In this article, we characterize the effect of probucol on cellular ABCA1-mediated lipid efflux. METHODS AND RESULTS Probucol inhibited cholesterol efflux up to 80% in J774 macrophages expressing ABCA1. In Fu5AH hepatoma cells that contain scavenger receptor class B, t...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2004
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000148706.15947.8a